宋智勇，男，中共黨員，副教授，理學博士，近年來主要圍繞智能化納米材料的設計與可控制備，用于藥物的定點、可控釋放，以耐藥性細菌為研究對象，開展納米化學生物學效應研究。目前以第一作者或通訊作者在Nature Communications，Advanced Functional Materials, Small，Biomaterials，Chemical engineering journal，ACSAppliedMaterials &Interfaces，Environmental Science: Nano，Chemical Communications等國際學術期刊上發表論文13篇，其中影響因子大于10的論文5篇，大于5的論文9篇。目前主持國家自然科學，77779193永利官网校自主創新基金等多項基金。

研究領域

（1）納米材料的設計與可控制備，用于藥物分子的定點、可控釋放；

（2）無抗生素納米載藥系統的構建及其針對超級細菌感染治療；

科研項目

（1）國家自然科學基金委員會，青年項目，21807036，跨血腦屏障CRISPR/Cas13a遞送系統的構建及其對狂犬病的治療研究，2019年01月至2021年12月，27.5萬，在研；

（2）77779193永利官网自主創新基金，培育專項，2662020LXPY007，細胞膜仿生納米平台構建及其用于幽門螺旋杆菌靶向治療研究，2020年05月至2023年4月，21萬，在研；

（3）77779193永利官网，教師啟動基金，納米材料介導的單克隆抗體細胞内遞送及協同抗病毒治療，2016年09月至2019年8月，15萬，結題。

近5年代表性論文

（1）YangWu^#,ZhiyongSong^#, HuajuanWang, HeyouHan* Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infectionsNature communications, 2019, 10 (1), 1-10.

（2）ZhiyongSong^#, YangWu^#, QiCao, HuajuanWang, XiangruWang, HeyouHan*.pH‐Responsive, Light‐Triggered on‐Demand Antibiotic Release from Functional Metal–Organic Framework for Bacterial Infection Combination Therapy,Advanced Functional Materials, 2018, 28 (23), 1800011.

（3）YangWu, GuiyunDeng, KaiJiang, HuajuanWang,ZhiyongSong*, HeyouHan*. Photothermally triggered nitric oxide nanogenerator targeting type IV pili for precise therapy of bacterial infections,Biomaterials, 2020, 120588.

（4）HuajuanWang^#, JinZhang^#,ZhiyongSong^#, YongliMu, MF Foda, YangWu, HeyouHan.An intelligent platform based on acidity-triggered aggregation of gold nanoparticles for precise photothermal ablation of focal bacterial infection,Chemical Engineering Journal, 2020, 127076.

（5）ZhiyongSong, XiaoyuWang*, GenxinZhu, QinggongNian, HangyuZhou, DongYang, ChenfengQin, RuikangTang*.Virus Capture and Destruction by Label‐Free Graphene Oxide for Detection and Disinfection Applications,Small, 2015, 11 (9-10), 1171-1176.

（6）ShuojunLi^#,ZhiyongSong^#, CaiyunLiu, XiaolinChen*, HeyouHan*.Biomimetic Mineralization-Based CRISPR/Cas9 Ribonucleoprotein Nanoparticles for Gene Editing,ACS Applied Materials & Interfaces, 2019, 11 (51), 47762-47770

（7）JunMa^#,ZhiyongSong^#, JianhongYang, YouningWang, HeyouHan*.Cobalt Ferrite Nanozyme for Efficient Symbiotic Nitrogen Fixation via Regulating Reactive Oxygen Metabolism,Environmental Science: Nano, 2020.

（8）ZhiyongSong^#, YangWu^#, HuajuanWang, HeyouHan*. Synergistic antibacterial effects of curcumin modified silver nanoparticles through ROS-mediated pathways,Materials Science and Engineering: C, 2019, 99, 255-263.

（9）ZhiyongSong, LongLiu, XiaoyuWang, YongqiangDeng, QingongNian, GuanchuanWang, ShunyaZhu, XiaofengLi, HangyuZhou, TaoJiang, XurongXu, RuikangTang*, ChenfengQin*. Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection,Chemical Communications, 2016, 52(9): 1879-1882.